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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KSR2
All Species:
7.27
Human Site:
S344
Identified Species:
16
UniProt:
Q6VAB6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VAB6
NP_775869.3
950
107632
S344
L
N
L
K
I
H
S
S
V
G
S
C
E
N
I
Chimpanzee
Pan troglodytes
XP_001145739
986
111275
S320
L
N
L
K
I
H
S
S
V
G
S
C
E
N
I
Rhesus Macaque
Macaca mulatta
XP_001083311
805
90894
K268
R
D
L
G
N
S
I
K
H
R
F
S
T
K
Y
Dog
Lupus familis
XP_853953
898
99758
V338
P
H
G
S
P
Q
M
V
R
R
D
I
G
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVC0
959
108554
G345
L
N
L
K
I
H
S
G
V
G
S
C
E
N
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514916
259
29171
Chicken
Gallus gallus
Q04982
806
89347
H269
Q
T
C
G
Y
K
F
H
Q
R
C
S
T
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137513
942
106704
S342
L
N
L
K
I
H
S
S
V
A
G
S
C
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11346
782
88616
L245
W
H
T
D
I
G
T
L
H
V
E
E
I
F
V
Honey Bee
Apis mellifera
XP_393005
895
100160
L318
D
I
T
G
E
N
L
L
L
N
S
N
S
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
F284
D
R
R
S
D
P
A
F
K
E
L
H
N
R
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
84.3
51
N.A.
95.5
N.A.
N.A.
25.1
24.3
N.A.
82.3
N.A.
24.9
36.4
N.A.
N.A.
Protein Similarity:
100
92.1
84.5
64.6
N.A.
97
N.A.
N.A.
26.3
40.2
N.A.
90.1
N.A.
40.9
53.5
N.A.
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
93.3
N.A.
N.A.
0
0
N.A.
60
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
13.3
6.6
N.A.
93.3
N.A.
N.A.
0
6.6
N.A.
60
N.A.
26.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
10
28
10
0
0
% C
% Asp:
19
10
0
10
10
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
10
10
10
28
19
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
10
0
0
10
0
% F
% Gly:
0
0
10
28
0
10
0
10
0
28
10
0
10
0
0
% G
% His:
0
19
0
0
0
37
0
10
19
0
0
10
0
0
0
% H
% Ile:
0
10
0
0
46
0
10
0
0
0
0
10
10
0
28
% I
% Lys:
0
0
0
37
0
10
0
10
10
0
0
0
0
10
0
% K
% Leu:
37
0
46
0
0
0
10
19
10
0
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
37
0
0
10
10
0
0
0
10
0
10
10
28
10
% N
% Pro:
10
0
0
0
10
10
0
0
0
0
0
0
0
10
0
% P
% Gln:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
10
10
0
0
0
0
0
10
28
0
0
0
10
0
% R
% Ser:
0
0
0
19
0
10
37
28
0
0
37
28
10
0
10
% S
% Thr:
0
10
19
0
0
0
10
0
0
0
0
0
19
0
0
% T
% Val:
0
0
0
0
0
0
0
10
37
10
0
0
0
0
37
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _